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MNEOS · Humans and AI, building the future together

The brightest minds, human and artificial, working on what matters most.

MNEOS unites human scientists and engineers with artificial intelligence, and soon with embodied AI and humanoid robotics, to take on the hardest problems in health, engineering and knowledge. Every experiment we run teaches the next one, because we built the memory to make sure it does.

Founded and led by David Sherrer. The first Neuroclearance bench prototype is being built right now, its public site and open brain-health library are live at neuroclearance.com, and we are looking for the people who want to shape the experiments that follow.

  1. Questionand the existing evidence
  2. Model and predictionrecorded before the test
  3. Measurementwith stated conditions
  4. Compare, then decidea person is responsible for the decision
  5. Recordsource, decision, what changed

The record feeds the next question, so each experiment starts with more understanding than the last.

Illustration. How one question, one measurement and one decision connect in the MNEOS method, so the next experiment starts smarter. Bench photographs follow as the build progresses.

Three fronts

Where the work is happening now

Brain health and healthy aging

Neuroclearance

Can a better understanding of brain physiology lead to useful approaches to brain health, recovery and healthy aging?

We are building the instruments to understand how the brain clears, repairs and sustains itself, so that understanding can become better lives. The first bench prototype is being built now, and the program's public site teaches the science behind it.

Bench prototype in development

Latest: Public site and brain-health library launched at neuroclearance.com (October 2026)
Updated: October 10, 2026

Open the program page · Visit neuroclearance.com

Scientific AI and memory

Scientific AI and memory

Can a research system answer what changed, show where that answer came from and preserve what a human decided to do about it?

AI that remembers why. We are building DOS, a memory that keeps every source, decision and lesson, so human and machine intelligence can compound across every project instead of starting over.

Capability-specific development

Latest: Capability inventory published with scoped status (September 2026)
Updated: September 28, 2026

Open the program page

Materials, manufacturing and testing

Physical engineering

How should measured results change a model, a material choice and the next experiment?

Ideas have to survive the physical world. Through related programs in materials, manufacturing and testing, we put models and AI to work on real hardware, then build the embodied systems that will do it alongside us.

Related programs operated by MacroVation and Helicon Defense; MNEOS method development

Latest: Operating organizations and MNEOS roles identified for each example (September 2026)
Updated: September 28, 2026

Open the program page

The vision

Human minds, artificial minds and embodied intelligence, one team

We believe the next great leaps in science and engineering will come from teams of human and artificial minds working as one: people bringing judgment, creativity and purpose; AI bringing tireless search, synthesis and computation; and embodied AI and humanoid robots bringing hands to the laboratory and the factory floor.

MNEOS is where that team is being assembled. The memory is DOS, so nothing learned is ever lost. The proving ground is real hardware, from a brain-health bench instrument to advanced manufacturing lines. The measure of success is simple: does the next experiment start smarter than the last?

The road ahead

Now. A human founder and AI collaborators working daily on Neuroclearance, DOS and physical engineering. Most of the day-to-day research, drafting, design iteration and software is done by AI under human direction and review.

Next. Instruments and manufacturing cells that AI can operate under human direction, with every run recorded and learned from.

Then. Embodied AI and humanoid robotics working alongside people in the lab and on the line, as full members of the team.

A vision we are building toward, one tested milestone at a time.

Proof in practice

Neuroclearance: built with AI, decided by people

Neuroclearance is the clearest example so far of the MNEOS method at work. The founder sets the questions, the standards and the decisions. AI collaborators do most of the rest, and DOS keeps the record of what was decided and why. In the founder's words, these days many of his most productive colleagues are not human.

What that has produced so far, with every item reviewed by a person before release:

  • The science, read and synthesized. Hundreds of primary sources on brain clearance, energy, vascular health, aging and neuroplasticity, distilled into an open, source-cited library of eighteen plain-language explainers at neuroclearance.com/learn.
  • The engineering, explored and documented. Component selection, design trade studies, safety concept and test planning for the first bench instrument, drafted with AI and decided by the founder.
  • The public face, designed and built. The NeuroClearance identity, website and printed materials were designed, written, built and deployed in a human–AI collaboration over a matter of days.
  • The memory, kept. Every decision, source and revision lives in DOS, so the next person or system to join the program starts with the whole story rather than a summary of it.

Division of labor today

People decide. Questions, standards, safety, what gets published, and what the measurements mean.

AI does. Literature synthesis, drafting, design exploration, analysis, software and site construction, at a pace a small human team could not match.

DOS remembers. Sources, decisions and lessons, so nothing has to be rediscovered.

Stated plainly because we think it is the future of small, serious research institutions, and because readers deserve to know how the work was made.

How NeuroClearance describes itself

How the work advances

Every experiment makes the next one better

Our method is simple to say and demanding to do: start from a question worth answering, bring every piece of evidence to bear, let people and AI explore the possibilities together, test the idea against the physical world, and keep the whole story so the next experiment starts smarter.

  1. Ask a bold questionState what we want to know and what would count as an answer.
  2. Gather the evidenceEverything already known, with its sources, so we start ahead.
  3. Model and designHumans and AI explore the possibilities together and choose the test that will teach us most.
  4. Build and testReal hardware, real conditions, results recorded as they happen.
  5. Remember and improveThe result, the decision and the reasons are kept, so the next person starts smarter.

People lead. AI amplifies. Measurements decide.

See how we work →

Founder

A new venture built on decades of building

David Sherrer has spent his career turning hard technology into things people can build and use: founding Haleos and Nuvotronics, taking new microfabrication from concept to production and acquisition, and leading defense and manufacturing programs since. MNEOS is his answer to a question he could not stop asking: how much more could a small team accomplish if human insight, AI and a memory that never forgets worked together from day one?

Where we are. MNEOS is founder-led today. Its day-to-day work is carried out with AI collaborators, and it is growing into a community of people. The people who join now will shape what it becomes.

Meet David   The track record →

One ecosystem

NuvoNexus, LLC is the operating home of MNEOS and DOS.

NeuroClearance is the brain-health research program, with its own public site and open library at neuroclearance.com.

MacroVation builds and manufactures: foam systems, sleep-surface materials and naval components for U.S. defense customers.

Helicon Defense brings allied battlefield innovation into trusted U.S. production.

Each does its own work. MNEOS is where the method and the memory come together.

Field notes

What changed in the work

· Test-plan explanation

What a trustworthy prototype must demonstrate first

Four properties every serious instrument earns before it earns a claim: repeatability, timing, calibration and honest fault handling. This is the standard we are building to.

All field notes →

Join us

Bring a hard question, or the skill to answer one

If you can improve a model, challenge an assumption, build an instrument, write software that remembers, or design a better experiment, there is a place for you here. Start with a problem that excites you and tell us what you would bring.

The ideas behind MNEOS →